Naslov
DEVELOPMENT OF EPISTATIC VARIANCE COMPONENTS IN THE TWO LOCUS BI-ALLELIC MODEL

Autori
Čurik, Ino ; Sölkner, Johann ; Kapš, Miroslav

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Final programme and Book of abstract Second congress of Croatian geneticists / Franekić Čolić, Jasna ; Ugarković, Đurđica - Zagreb : Hrvatsko genetičko društvo, 2005

Skup
Second congress of Croatian geneticists

Mjesto i datum
Supetar, Hrvatska, 24.09.2005. - 27.09.2005

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
development of epistatic variance; bi-allelic model

Sažetak
Estimation of variance components for a quantitative trait is very difficult when genetic interactions between loci can not be neglected. The presence of interactions, even among few loci, very soon becomes extremely complicated due to the large number of possible combinations. Here, we presented development of variances components in the simplest model that includes epistatic effects (two locus bi-allelic model) for a population that is in Hardy-Weinberg equilibrium. The presented formulas enable three dimension graphical presentations of all variance components (including additive by additive, additive by dominance and dominance by dominance variances) under different models for all possible gene frequencies and can be used in scholastic purposes. Further, these formulas are also suitable for Monte Carlo based studies related to deviations of the observed from theoretical values (for example the effects of inbreeding on epistatic variances) as well as for further developments in segregation analyses related to two loci models and epistatic effects.

Izvorni jezik
Engleski

Znanstvena područja
Poljoprivreda (agronomija), Biotehnologija

POVEZANOST RADA