Naslov
Comparative analysis of azithromicn and ciprofloxacin in the treatment of chronic prostatitis

Autori
Škerk, V. ; Schonwald, S. ; Mareković, Z. ; Banaszak, A. ; Begovac, J. ; Strugar, J. ; Strapać, Z. ; Vrsalović, R. ; Vuković, J. ; Tomas, M.

Izvornik
Internationa Journal of Antimicrobial Agents (0924-8579) 21 (2003), 5; 457-462

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
chronic prostatitis; Chlamydia trachomatis; antibiotics

Sažetak
A total of 89 patients, (>18 years), with symptoms of chronic prostatitis and inflammatory findings as well as the presence of Chlamydia trachomatis confirmed by DNA/RNA DIGENE hybridization method and/or by isolation, McCoy culture and Lugol stain in expressed prostatic secretion or in voided bladder urine collected immediately after prostatic massage, were examined. The patients were randomized to receive a total of 4.5 g of azithromycin for 3 weeks, given as a 3-day therapy of 1 x 500 mg weekly or ciprofloxacin 500 mg b.i.d. for 20 days. Patients' sexual partners were treated at the same time. Clinical and bacteriological efficacy were evaluated 4-6 weeks after the end of therapy. Significantly higher eradication (36/45: 17/44 ; P=0.0002) and a significantly higher clinical cure (31/45: 15/44 ; P=0.0021) were achieved in the group of patients treated with azithromycin than in the ciprofloxacin group.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA