Naslov
The role of dopamine in the formation of gastric ulcers in rats

Autori
Sikirić, Predrag ; Geber, Juraj ; Suchanek, Ernest ; Ivanović, Drago ; Gjuriš, Veljko ; Aleksić, Jelena ; Reić, Petar ; Marović, Anton

Izvornik
European journal of pharmacology (0014-2999) 112 (1985); 127-128

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Dopamine agonists; Dopamine antagonists; Gastric ulcer

Sažetak
A single dose of the dopamine agonists L-dopa, bromocriptine or apomorphine produced a protective effect by significantly shortening of the length of stomach ulcerations. A single dose of the dopamine antagonists haloperidol, sulpiride or domperidone potentiated the ulcerogenic effect by extending the length of stomach ulcerations. These results point to the fact that dopamine is involved in the rise and development of experimental stomach ulcers.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA