Pregled bibliografske jedinice broj: 22087
The effect of microfluidization of protein-coated liposomes on protein distribution on the surface of generated small vesicles
The effect of microfluidization of protein-coated liposomes on protein distribution on the surface of generated small vesicles // Biochimica et Biophysica Acta. Lipids and Lipid Metabolism, 1301 (1996), 3; 249-254 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 22087 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
The effect of microfluidization of protein-coated liposomes on protein distribution on the surface of generated small vesicles
Autori
Škalko, Nataša ; Bouwstra, Joke ; Spies, Ferry ; Gregoriadis, Gregory
Izvornik
Biochimica et Biophysica Acta. Lipids and Lipid Metabolism (0005-2760) 1301
(1996), 3;
249-254
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
liposome; tetanus toxoid; immunoglobulin G; covalent souplilng; microfluidization
Sažetak
Tetanus toxoid and immunoglobulin G (IgG), model proteins for vaccines and targeting ligands respectively, were covalelntly coupled to preformed dehydration-rehydration vesicles (DRV) to produce vesicles with surface-bound proteins (DRV-protein) or to preformed small unilamellar vesicles (SUV) which were used to generate DRV with bound protein ((SUV-protein)DRV). These studies were supplemented with freeze-fracture electron microscopy of (SUV-toxoid)DRV which demostrated the presence of proteinparticles (up to 3 ; 12-14 nm diameter) on the surface of both intact and microfluidized individual liposomes.
Izvorni jezik
Engleski
Znanstvena područja
Farmacija
POVEZANOST RADA
Projekti:
006250
Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb
Profili:
Nataša Škalko-Basnet
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Scopus
Uključenost u ostale bibliografske baze podataka::
- CA Search (Chemical Abstracts)
