Naslov
LYMPHADENOPATHY: DIAGNOSTIC AND CLINICAL CONTROVERSY

Autori
Jakšić, Branimir

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, pp prezentacija, ostalo

Izvornik
Knjiga sažetaka / Jonjić, Nives ; Kardum-Skelin, Ika - Zagreb, 2005

Skup
3. Hrvatski kongres kliničke citologije s međunarodnim sudjelovanjem

Mjesto i datum
Opatija, Hrvatska, 08.05.2005. - 11.05.2005

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Nije recenziran

Ključne riječi
lymphadenopathy; controversy

Sažetak
Lymphadenopathy is traditionally one of the most intriguing diagnostic and clinical problems. The unprecedented development of new technologies in recent years has tremendously improved the power of diagnostics in hematological clinical practice leading to development of new fields that require expertise, in addition to traditional cytological and/or histological morphology. By the same token, new abilities to classify disorders have considerably contributed to information noise in diagnostic procedures and clinically relevant classification. The potential of an individual technique (such as morphology, immunology, flow cytometry, cytogenetics, molecular characterization, imaging techniques etc.) to reliably classify patients is much higher then is usually converted into clinical benefit. This is due to the fact that systematic clinical research in evaluation of complex approaches by using various diagnostic techniques is as a rule coming later then description of individual technique. The apparent controversies that are to be expected in this multidimensional network sometimes discourage investigators to confront different approaches and validate the process in methodologically sound clinical research setting. Instead, certain &laquo ; ; rivalry&raquo ; ; among disciplines emerges, so that evidence based approaches give place to opinion based approaches, causing a number of controversies that we witness today. Moreover, precise diagnostic procedures are today even more important then before, since smart drugs, and targeted therapies require precise and reliable definition of underlying disorder. Various diagnostic approaches that are available have different risk, cost, reliability, consistency, sensitivity and specificity. Therefore, clinical research of diagnostic procedures of this growing field is to be encouraged to provide more clinical benefit. Thus, with the knowledge gathered already certain traditional diagnostic dogmas could be amended or changed to improve the efficacy of bedside care.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA