Pregled bibliografske jedinice broj: 217280
Isolation and characterisation of senescent cells from immortal human cell line MDA-MB-231
Isolation and characterisation of senescent cells from immortal human cell line MDA-MB-231 // Second congress of croatian geneticists
Supetar, Hrvatska, 2005. (poster, nije recenziran, sažetak, znanstveni)
CROSBI ID: 217280 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Isolation and characterisation of senescent cells from immortal human cell line MDA-MB-231
Autori
Ćukušić, Andrea ; Ivanković, Milena ; Gotić, Ivana ; Rubelj, Ivica
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Skup
Second congress of croatian geneticists
Mjesto i datum
Supetar, Hrvatska, 24.09.2005. - 27.09.2005
Vrsta sudjelovanja
Poster
Vrsta recenzije
Nije recenziran
Ključne riječi
MDA-MB-231 cells; telomerase; cell senescence; DiI
Sažetak
Normal human somatic cells have a limited division potencial when they grow in vitro. That happens due to the shortening of telomeres. immortal cell line MDA-MB-231 has an active telomerase, which stops telomere shortening and allows permanent division.In that cell line is documentated some percentage of cells that do not divide during a few days time of growth in culture. It can be concluded that the stop of division of some cells of immortal MDA-MB-231 cell line, like in the case of some other tumor cells, is a consequense of great genomic instability.
Izvorni jezik
Engleski
Znanstvena područja
Biologija
