Naslov
Infections associated with blood transfusion

Autori
Begovac, Josip

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
1. kongres hrvatskog društva za unapređenje beskrvnog liječenja s međunarodnim sudjelovanjem / - Zagreb, 2005

Skup
1. kongres hrvatskog društva za unapređenje beskrvnog liječenja s međunarodnim sudjelovanjem

Mjesto i datum
Zagreb, Hrvatska, 22.09.2005. - 25.09.2005

Vrsta sudjelovanja
Pozvano predavanje

Vrsta recenzije
Nije recenziran

Ključne riječi
-

Sažetak
Out of an estimated 75 million units of blood collected in the world annually, at least 13 million are incompletely screened for viral infections, including almost half in resource-poor countries. The advent of the epidemic of human immunodeficiency virus in the 1980s, followed by hepatitis C and, more recently, by outbreaks of West Nile virus, Creutzfeldt-Jakob variant disease, and the severe acute respiratory syndrome, has continued to draw attention to the safety of the blood supply. Bacteria also are transmitted by transfusion, often with catastrophic results. We studied the case of a regular blood donor who transmitted HIV-1 to a recipient of platelets and a recipient of plasma in Croatia in 2004. The transmission was detected by a look-back investigation performed because of HIV-1 seroconversion of the blood donor by the time of the next donation. Plasma collected at the time of the donation, tested negative with the use of the Roche Amplicor HIV-1 Monitor UltraSensitive Method with a detection limit of 50 HIV-1 RNA copies per milliliter. Thus, complete elimination of risk is not achievable and implementation of additional measures should be subject to consideration of cost-effectiveness in a global context.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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