Naslov
Urogenitalna atrofija u postmenopauzi
(Urogenital atrophy in postmenopause)

Autori
Šprem, Marina ; Pavičić Baldani, Dinka ; Šimunić, Velimir

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Skup
3rd Slovene - Croatian Symposium on Menopause and Andropause with Interactive Workshop

Mjesto i datum
Rogaška Slatina, Slovenija, 07.04.2005. - 09.04.2005

Vrsta sudjelovanja
Pozvano predavanje

Vrsta recenzije
Nije recenziran

Ključne riječi
urogenitalna atrofija; lokalna terapija estrogenima
(urogenital symptoms; local estrogen treatment)

Sažetak
The overall success rate of micronized 17 -estradiol on subjective and objective symptoms of postmenopausal women with vaginal atrophy was 85.5%, and the effect of placebo was 41.4%. A significant improvement of urinary atrophy symptoms was determined in vaginal ERT group comparing with the beginning of the study (51.9% vs. 15.5%, p=0.001). Maximal cystometric capacity and the volume of the urinary bladder at which patients first felt urgency and strong desire to void were considerably larger after micronized 17 -estradiol treatment than before it. The number of patients with uninhibited bladder contractions significantly decreased after micronized 17 -estradiol compared with the values before the treatment or after placebo. Side effects were observed in 61 (7.8%) patients treated with low dose micronized 17- estradiol. We found that 25  g of micronized 17- estradiol do not raise serum estrogen level and do not stimulate endometrial growth.

Izvorni jezik
Hrvatski

Znanstvena područja
Kliničke medicinske znanosti

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