Naslov
Procjena funkcionalnog statusa tijekom terapije beta interferonom
(Evaluation of functional status during Beta interferon therapy)

Autori
Lisak, Marijana ; Trkanjec, Zlatko ; Bošnjak Pašić, Marija ; Demarin, Vida

Izvornik
Acta clinica Croatica (0353-9466) 44 (2004); 11-15

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
multipla skleroza; beta interferon; funkcionalni status
(multiple sclerosis; beta interferon; therapy; functional status)

Sažetak
Summary Twenty patients (11 females and 9 males) with remitting relapsing-multiple sclerosis (RRMS) were treated with beta interferon at University Department of Neurology, Sestre milosrdnice University Hospital. Thirteen patients were treated with interferon beta-1a (6 MIU 3 times weekly) and seven patients with interferon beta-1b (9, 6 MIU every other day). The Expanded Disability Status Scale (EDSS) was recorded before interferon therapy and six months after initiation of interferon therapy. Average EDSS score was slightly smaller after six months of interferon therapy in both groups, but the difference was not statistically significant (p=0.17 in interferon beta-1a group and p=0.36 in interferon beta-1b group). Results in this small group of patients showed early improvement in functional status in MS patients during interferon therapy. Further follow-up is required to get additional information about the course of functional improvement in MS patients during interferon therapy after longer period of time.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA