Pregled bibliografske jedinice broj: 215085
Central administration of alloxan imapirs glucose tolerance in rats
Central administration of alloxan imapirs glucose tolerance in rats // Journal of neural transmission, 112 (2005), 10; 1391-1395 doi:10.1007/s00702-005-0360-y (međunarodna recenzija, kratko priopcenje, znanstveni)
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Naslov
Central administration of alloxan imapirs glucose tolerance in rats
Autori
Šalković-Petrišić, Melita ; Lacković, Zdravko ; Hoyer, Siegfried ; Riederer, Peter
Izvornik
Journal of neural transmission (0300-9564) 112
(2005), 10;
1391-1395
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, kratko priopcenje, znanstveni
Ključne riječi
Alloxan; Intracerebroventricular; Glucose; Insulin
Sažetak
By means of oral glucose tolerance test (OGTT), we investigated glucose tolerance in rats pre-treated with intracerebroventricular and subcutaneous non-diabetogenic dose of betacytotoxic drug alloxan 7 days before OGTT. Being normoglycemic and normoinsulinemic pre-OGTT, at 30 minutes post-OGTT, alloxan intracerebroventricularly-treated rats had a lower glucose and a higher insulin plasma levels in comparison with controls or alloxan subcutaneously treated animals. Centrally administered alloxan seems to have within the brain effect on the regulation of peripheral glucose tolerance and insulin secretion.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
