Naslov
COMPARISON OF MUCINOUS AND NON-MUCINOUS COLORECTAL CARCINOMAS

Autori
Baličević, Drinko ; Tomas, Davor ; Leniček, Tanja ; Rajačić, Nada ; Rožanković, Vesna ; Reljica-Kostić, Zlata ; Belicza, Mladen

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Acta clinica croatica / Kusić Z - Zagreb : Birotisak, 2005, 231-232

Skup
16th Ljudevit Jurak International Symposium on Comparative Pathology

Mjesto i datum
Zagreb, Hrvatska, 03.06.2005. - 04.06.2005

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
Mucinous colorectal cancer; Nonmucinous colorectal cancer

Sažetak
AIM: Mucinous colorectal carcinomas differ from nonmucinous in some clinicopathological characteristics. In some authors&#8217; opinions, these tumors have a predilection for younger age groups, there is no male predomination and are more advanced at the time of diagnosis. The study aims to examine differences in colorectal carcinomas depending on mucinous content. MATERIAL AND METHODS: Patients&#8217; data were obtained from the computer based colorectal carcinoma registry established at our Department, for the period between January 1, 2000 and December 31, 2004. A total of 1091 patients suffering from colorectal carcinoma were analyzed and divided into 3 groups according to the presence or absence of mucinous content: mucinous carcinomas (>50% of mucin), colorectal carcinomas with mucin (< 50% of mucin) and nonmucinous colorectal carcinomas. Sex and age distribution, localization, Dukes stage and T and N status were observed within all of these three groups. RESULTS: From the total of 117 663 biopsies done between the years 2000 and 2004 there was a total of 1091 colorectal carcinomas among which: 837 (76.7%) nonmucinous, 169 (15.5%) with mucin and 85 (7.8%) mucinous. The male/female ratio was lower in groups with mucinous carcinomas (1, 1) and carcinomas with mucin (1.0), comparing to 1, 5 in group of patients suffering with nonmucinous colorectal carcinoma. The average age of patients with nonmucinous cancer was 66.1 years, and 68.1 and 65.4 in following two groups. Mucinous carcinomas and carcinomas with mucin were found to involve more proximal colon (44.4% and 33.5% are right-sided) then nonmucinous (only 18.2% of right-sided). Analyzing the Dukes stages we found 235 cases (38.3%) of C stage in group of patients with nonmucinous cancer, followed by 70 cases (44.3%) of C stage in group of colorectal carcinoma with mucin and 46 cases (56.8 %) in group with mucinous carcinoma. In addition, 85.5% of mucinous carcinomas were in T3 and T4 opposing 73.1% of nonmucinous found in the same stages. 40.7% of mucinous carcinomas were diagnosed in the status N0 opposing 57.0% of nonmucinous colorectal carcinoma. CONCLUSION: Mucinous carcinomas showed no male predomination, higher incidence in the proximal colon and higher Dukes stages and T and N status. Predilection for younger age groups was not established, although the average age of patient with mucinous colorectal carcinoma was found to be a slightly lower.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA