Naslov
Naša iskustva u liječenju raka bubrega i prostate u zadnjih 10 godina
(Our experiences in treatment of renal parenchyma cancer and prostate cancer in last 10 years)

Autori
Šimunović, Dalibor ; Galić, Josip ; Tucak, Antun

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
Treći hrvatski urološki kongres. Knjiga sažetaka / - , 2005

Skup
The Thrid Croatian Urological Congress with International Participation

Mjesto i datum
Osijek, Hrvatska, 21.09.2005. - 24.09.2005

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
rak bubrega; rak prostate; epidemiologija
(kidney cancer; prostate cancer; epidemiology)

Sažetak
Introduction As the population is getting older we are facing an increasing number of oncological patients. At the same time population is more and more fit to face advancing age with reduced co morbidity and better control of associated diseases found in older population. All this factors are responsible for facing urologist of today with increased number of oncological patients and radical procedures with its risks. Among those oncological illness a prostate cancer is enigma being in focus for decades and every time that we think that we now everything a new approach rises. Renal parenchyma tumors are in some ways a constant in everyday urological practice, but as such are reason for complete understanding of this malignant disease. Materials and methods Patients history, operating protocols, ambulance charts and other associated material of each operated patient at our clinic has been used. Basic revision of some record has been done such a TNM classification for some type of tumor due to new recommendations. We included in our analysis selected tumors: carcinoma of the prostate and parenchymal tumors of the kidney in last 10 years. Results 421 patient received treatment for prostate cancer with average age of 69 years. Of those orchydectomy was performed in 376 patients who are slightly older (69 years) then those in whom we did radical prostatectomy (45 patients with average age of 63, 5 years, 11% of all patients). T stage for selected patients in whom we did radical prostatectomy are T2 in 62%, T3 in 35% and T4 in 3%. Regional lymph node metastases were found in 7% of all patients. Gleason score for patients underwent orchydectomy and radical procedure is shown in table 1. Parenchyma renal tumor was found in 285 patients and of those clear cell carcinoma in 266 cases, followed by oncocitoma and some rare cases of lymphoma, sarcoma and even with rare case of mixed epithelial-stromal tumor of the kidney. There were 164 male patients and 121 female patients. We had 144 left sided tumors contra 141 rights sided. Radical nephrectomy was performed in 71 patients with average age of 56 years and simplex nephrectomy in 210 patients with average age of 62, 4 years. In only small number of cases a partial nephrectomy was performed. Average size of tumor was same for patients underwent simplex nephrectomy or radical nephrectomy: 7, 1 cm. TNM classification for all cases is shown in table 2. Only limited number of major complications is seen: no mortal outcome is seen in prostate cancer patients, and 2 deaths postoperatively for patients with radical nephrectomy. Discussion When we look patients with prostate cancer a high rate of orchidectomy is seen. Reason for that can be found in fact that most of our patients are presented with metastasis disease (verified on bone scan) or with locally advanced prostate cancer with high PSA levels (1, 3). Some attempts have been made to start prostate cancer screening in our country. This efforts are having as result a increased number of radical procedures , for example in year 2000 we had 5 radical operations, in 2004 13, and so far in 2005 we have 15 operations. Also it can be seen from table 1. that indication for radical procedure are well set. Other variables are not different with those reported in literature (1, 3, 4). Same can be told for renal cancers in whom a late diagnosis or high co-morbidity is by our opinion a main reason for limited number of radical nephrectomy (1, 2). Most of our patients are presented with locally advanced disease or with distant metastasis. Co- morbidity is second reason for limited number of radical operations, since a vast number of our patients are found unfit for radical procedures by our anesthesist.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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