Naslov
High prevalence of positive skin prick test in Croatian urban school children

Autori
Pevec Branko, Stipić-Marković Asja, Radulović Pevec Mira, Turkalj M, Zimić L

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Journal of the World Allergy Organization, Abstracts / Baena-Cagnani C.E., Wahn U. - Göttingen : Hogrefe & Huber Publishers, 2005

Skup
XIX World Allergy Organization Congress, XXIV EAACI Congress

Mjesto i datum
München, Njemačka, 26.06.2005. - 01.07.2005

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
allergy; wheezing; rhinitis; egzema

Sažetak
BACKGROUND The purpose of this study was to determine the prevalence of positive skin tests to inhalation allergens in a school population of Zagreb. Previously we have shown that the prevalences of allergic symptoms according to ISAAC questionnaires applied to the same school population, was low (12-month prevalences of wheezing, allergic rhinitis, and atopic eczema symptoms were 6.02%, 12.13%, and 7.83% respectively). METHOD Skin prick tests (SPT) with 10 common inhalation allergens from Alk-Abello (Dermatophagoides pteronyssinus, Dermatophagoides farinae, Cat, Dog, Mixed grasses, Mixed trees, Ambrosia trifida, Alternaria tenuis, Cladosporium herbarum, and Cockroach) were performed in 13-year-old children (7th grade) attending 18 elementary schools in a city of Zagreb. A total number of 384 children, whose parents signed the informed consent, were included. SPTs were performed according to recommendations of ISAAC Steering Committee. RESULTS A positive SPT was recorded in 52.34% (n=201) of the total number of children (n=384). The girls had a slightly greater prevalence of positive SPT (53.77%) than the boys (50.58%), but without statistically significant difference (χ 2=3.62, p=0, 057). Looking at the number of positive allergens in a SPT, we found that 29.35% (n=59) of children had sensitization to one allergen, 18.90% (n=38) were sensitized to two allergens, and 51.74% (n=104) were sensitized to three or more allergens. Prevalences of sensitization to particular allergens were as follows: 56.22% (n=113) to D. pteronyssinus, 39.80% (n=80) to D. farinae, 35.82% (n=72) to cat, 36.31% (n=73) to dog, 29.35% (n=59) to trees, 40.30% (n=81) to grasses, 32.83% (n=66) to A. trifida, 16.91% (n=34) to A. tenuis, 12.43% (n=25) to C. herbarum, and 17.41% (n=35) to cockroach. CONCLUSION High prevalence of atopic sensitization is surprising as the reported symptom prevalences were relatively low. Another surprising finding is a high prevalence of polysensitized children. Main sensitizing allergens are house dust mites and grass pollens, followed by dog, cat, ambrosia, tree pollens, and with somewhat lower prevalence cockroach and moulds. A larger sample and comparison with questionnaire results are intentions for a future work.

Izvorni jezik
Engleski

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