Pregled bibliografske jedinice broj: 210155
Enantiomers and Barriers to Racemization of Sterically Hindered N-Aryl- and N-Heteroarylpyrroles
Enantiomers and Barriers to Racemization of Sterically Hindered N-Aryl- and N-Heteroarylpyrroles // Journal of heterocyclic chemistry, 29 (1992), 327-333 (međunarodna recenzija, članak, znanstveni)
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Naslov
Enantiomers and Barriers to Racemization of Sterically Hindered N-Aryl- and N-Heteroarylpyrroles
Autori
Vorkapić-Furač, Jasna ; Mintas, Mladen ; Kastner, Fritz ; Mannschreck, Albrecht
Izvornik
Journal of heterocyclic chemistry (0022-152X) 29
(1992);
327-333
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
N-aryl- and N-heteroaryl-2; 5-dimethylpyrrole-3-carbaldehydes; Enrichment of the enantiomers M and P; liquid chromatography on triacetylcellulose; barrier to partial rotation about the C-N bond
Sažetak
The N-aryl- and N-heteroaryl-2, 5-dimethylpyrrole-3-carbaldehydes 2-8 have been synthesized by condensation of hexane-2, 5-dione with the appropriate amine and subsequent Vilsmeyer-Haack formylation of the pyrrole ring. Diastereomeric association complexes of the racemic pyrrole 8 were studied by NMR chemical shifts and the splittings induced by (+)-1-(9-anthryl)-2, 2, 2-trifluoroethanol. Enrichment of the enantiomers M and P of 2 and 6 was achieved by liquid chromatography on triacetylcellulose. The barrier to partial rotation about the C-N bond in 6 was determined by thermal racemization and its lower limits in 2 and 8 were estimated.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
POVEZANOST RADA
Ustanove:
Fakultet kemijskog inženjerstva i tehnologije, Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
