Pregled bibliografske jedinice broj: 208472
Efficacy assessment of differential blood count on Bayer Advia 120 and Abbott Cell-Dyn hematologic analyzers (models 3200 and 4000)
Efficacy assessment of differential blood count on Bayer Advia 120 and Abbott Cell-Dyn hematologic analyzers (models 3200 and 4000) // Abstracts of the 15th IFCC-FESCC European Congress of Clinical Chemistry and Laboratory Medicine ; u: Clinical Chemistry and Laboratory Medicine 41 (2003) (S)
Barcelona, Španjolska, 2003. str. 144-144 (poster, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 208472 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Efficacy assessment of differential blood count on Bayer Advia 120 and Abbott Cell-Dyn hematologic analyzers (models 3200 and 4000)
Autori
Juričević, Mirjana ; Alpeza, Ines ; Zadro, Renata
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Abstracts of the 15th IFCC-FESCC European Congress of Clinical Chemistry and Laboratory Medicine ; u: Clinical Chemistry and Laboratory Medicine 41 (2003) (S)
/ - , 2003, 144-144
Skup
IFCC-FESCC European Congress of Clinical Chemistry and Laboratory Medicine (15 ; 2003)
Mjesto i datum
Barcelona, Španjolska, 01.06.2003. - 05.06.2003
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
differential blood count; hematology analyzer
Sažetak
The goal for a modern hematology instrument, besides the precise blood cell count, is to eliminate the need for technical review and microscopy in differential blood analysis. The aim of our study was to evaluate the differential performance of three hematology instruments and compare it with manual differential count. Analysis of differential blood count was performed on 150 inpatient randomized blood samples on three hematologic analyzers: Bayer Advia 120, Abbott Cell Dyn 4000 and 3200, along with manual differentiation. For comparison with microscopy method, truth table analysis was carried out for each instrument according to the criteria proposed by NCCLS. The results obtained for Advia 120, Cell Dyn 4000 and Cell Dyn 3200 were as follows (%): sensitivity: 96.9, 88.0 and 89.4, respectively, specificity: 67.0, 58.3 and 83.3, respectively ; efficacy: 60.1, 61.4 and 84.9, respectively. Inclusion of overview of scatterplot patterns as additional criterion in differential blood count assessment yielded equally acceptable sensitivity values: 98.4, 98.5 and 96.7, respectively, yet significantly lower values for specificity: 18.2, 29.4 and 38.0, respectively, and efficacy: 51.6, 67.3 and 61.4, respectively. In conclusion, high sensitivity of differential blood count assessment was obtained due to technological sophistication of instruments, whereas different values for specificity and efficacy were the result of different criteria determining the occurrence of signal in each instrument. The consequence of high sensitivity and low specificity of scatterplot pattern is the need for microscopy verification of results.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
