Naslov
History of Endemic Goiter in Croatia:From Severe Iodine Deficiency to Iodine Sufficiency

Autori
Kusić, Zvonko ; Jukić, Tomislav

Izvornik
Collegium antropologicum (0350-6134) 29 (2005), 1; 9-16

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
iodine deficiency disorders (IDD); endemic goiter; prevention; salt iodination; IDD status; Croatia; urinary iodine excretion; thyroid volume; schoolchildren

Sažetak
At the time after Second World War, endemic goiter was present in most parts of Croatia with a prevalence of more than 50% and presence of cretinism. In the village of Rude near Zagreb, goiter was detected in 85% of schoolchildren wuth 2, 3% of cretins in the village population.In 1953 the first regulation on obligatory salt iodination, requiiring 10 mg of potassium iodide(KI) per kg of salt was established in former Yugoslavia.A three-fold reduction of goiter prevalence, together with disappearance of cretinism was recorded ten years later. In 1992, the National Committee for Eradication of Goiter was founded.The survey performed during 1991-1993 exhibited prevalence of goiter among schoolchildren between 8% and 35 % and urinary iodine excretion inder 10ug/dL in most of the children from continental parts of the country. The new obligatory regulation, requiring 25 mg of KI/kg of salt, was proposed by the National Comittee and finally established in 1996. In 2002 thyroid volumes and medians of urinary iodine excretion were normal according to the ICCIDD criteria. Overall median of urinary iodine excretion for schoolchildren in Croatia was 14ug/dL.Croatia crossed a path from severe iodine deficiency detected in the 1950-s, to the period of mild to moderate iodine deficiency during the 1990-s, and finally, nowadays, iodine sufficiency has been achieved.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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