Naslov
CHIRAL RECOGNITION MECHANISM OF 1, 4-DIHYDROPYRIDINES ON AMYLOSE TRIS(3, 5-DIMETHYLPHENYL CARBAMATE) CHIRAL STATIONARY PHASE

Autori
Drušković, Vinka ; Litvić, Mladen ; Bartolinčić, Anamarija ; Šporec, Anita ; Vinković, Vladimir

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts / - Parma, 2005

Skup
Chirality 2005

Mjesto i datum
Parma, Italija, 11.09.2005. - 14.09.2005

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
1; 4-dihodropiridini; amylose; chiral recognition

Sažetak
Enantioseparation by liquid chromatography have considerably advanced during the past decade not only for determining optical purity but also for obtaining optically pure isomers. The understanding of chiral recognition mechanism at molecular level is of great importance in the field of chiral chromatography. Among the various chiral stationary phases (CSPs), the polysaccharide based CSPs are considered as the most efficient due to their wide range of applications in the field of chiral chromatography [1]. Although the numerous attempts have been made to predict the chiral recognition mechanism of these stationary phases at molecular level, the exact mechanism is still not known [2]. The work presented here deals with a group of chiral 1, 4-dihidropyridines (1, 4-DHPs), which are very important class of compounds because of their pharmacological activity as a calcium antagonists or agonists [3].

Izvorni jezik
Engleski

Znanstvena područja
Kemija

POVEZANOST RADA