Pregled bibliografske jedinice broj: 200747
The effect of neuroleptics on the GABA system of basal ganglia and the limbic cortex
The effect of neuroleptics on the GABA system of basal ganglia and the limbic cortex // Iugoslavica physiologica et pharmacologica acta, 14 (1978), 1; 201-203 (podatak o recenziji nije dostupan, članak, znanstveni)
CROSBI ID: 200747 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
The effect of neuroleptics on the GABA system of basal ganglia and the limbic cortex
Autori
Peričić, Danka
Izvornik
Iugoslavica physiologica et pharmacologica acta (0021-3225) 14
(1978), 1;
201-203
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
haloperidol; chlorpromazine; basal ganglia; limbic cortex; AOAA; GABA synthesis
Sažetak
Although one might expect that all neuroleptics, since they block dopamine receptors, increase the synthesis of dopamine and the firing rate of dopaminergic neurons, would cause a decrease in the activity of the striatonigral GABAergic pathway, this effect was found only after low doses of haloperidol. No obvious correlation between the apparent changes in GABA synthesis and the known effects of neuroleptics either on dopamine receptors or on the other neurotransmitter systems was observed.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
