Naslov
Androgenic/anabolic steroid-induced toxic hepatitis

Autori
Štimac, Davor ; Milić, Sandra ; Dobrila-Dintinjana, Renata ; Kovač, Dražen ; Ristić, Smiljana

Izvornik
Journal of clinical gastroenterology (0192-0790) 35 (2002), 4; 350-352

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, prikaz, stručni

Ključne riječi
toxic hepatitis; anabolic steroids

Sažetak
Athlets and bodybuilders often misuse androgenic/anabolic steroids. When used in therapeutic doses, these drugs produce clinical jaundice in just a small number of recipients. We present a 26-year old male bodybuilder who self-administered high doses of androgenic/anabolic steroids that induced liver damage.On admission, his bilirubin level was 470 micromol/L (direct, 360 micromol/L), his aspartat aminotransferase (AST) level was 5, 870 IU/L, his alanin aminotransferase (ALT) level was 10, 580 IU/L, his alkaline phosphatase (ALP) level was 152 IU/L, his gamma-glutamyl-transpeptidase level was 140 IU/L, his albumine level was 27.6 g/L, and his prothrombin time was 29%.During the patients prolonged hospitalization, multiple tests and liver biopsy were performed showing only toxic hepatic lesions.The patient was provided with supportive medical treatment.Clinical signs and laboratory findings improved substantially 12 weeks after the patient discontinued androgenic/anabolic sterodis.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA