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Pregled bibliografske jedinice broj: 19878

What do radon daughters tell us about Alzheimer's Disease, Parkinson's Disease, and the smoking habits? Selective distribution of trace elements in the diseased human brain indicate the impairment of Cl- ion membrane transport

Momčilović, Berislav; Alkhatib, A. Hassan; Duerre, A. John; Cooley, M. Alexander; Harris, T. Robert; Lykken, I. Glenn
What do radon daughters tell us about Alzheimer's Disease, Parkinson's Disease, and the smoking habits? Selective distribution of trace elements in the diseased human brain indicate the impairment of Cl- ion membrane transport // Mengen- und Spuren-Elemente. 17 Arbeitstagung 1997 / Anke, Manfred et al/ (ur.).
Leipzig: Verlag Harald Schubert, 1997. str. 574-588 (pozvano predavanje, međunarodna recenzija, cjeloviti rad (in extenso), znanstveni)

CROSBI ID: 19878 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
What do radon daughters tell us about Alzheimer's Disease, Parkinson's Disease, and the smoking habits? Selective distribution of trace elements in the diseased human brain indicate the impairment of Cl- ion membrane transport

Autori
Momčilović, Berislav ; Alkhatib, A. Hassan ; Duerre, A. John ; Cooley, M. Alexander ; Harris, T. Robert ; Lykken, I. Glenn

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni

Izvornik
Mengen- und Spuren-Elemente. 17 Arbeitstagung 1997 / Anke, Manfred et al/ - Leipzig : Verlag Harald Schubert, 1997, 574-588

Skup
Mengen und Spuren Element. 17. Arbeitstagung 1997, Friedrich Schiller Universitat, Jena

Mjesto i datum
Jena, Njemačka, 05.12.1997. - 06.12.1997

Vrsta sudjelovanja
Pozvano predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Alzheimer's Disease; Parkinson's Disease; smoking; environmental radon daughters; 210Bi; 210Po; brain proteins; brain lipids; Cl- membrane leakage; low risk radiation injury

Sažetak
We studied the accumulation of the environmental radon daughters, 210Bi and 210Po, in the lipid and protein fraction of gray and white matter from the frontal and/or temporal lobe of the suman brain from subjects with Alzheimer's Disease (AD), Parkinson's Disease (PD), and smokers, amd controls with no preious signs of clinical neurological disease. 210Bi and 210Po were primarily retained in the protein fraction from the cortical gray and subcortical white matter in the brains from AD and smokers and, in contrast, in the lipid fraction in PD. This accumulation was an order of magnitude higher than that of the controls. Free radicals generated by radioactive radon daughters are a potent source of injury to the brain astrocytes. The pathognomonic distribution of radon daughters in AD, PD, and smokers is attributed to the failure of Cl- ion membrane transport and leakage

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA

Projekti:
00220108

Ustanove:
Institut za medicinska istraživanja i medicinu rada, Zagreb

Profili:

Avatar Url Berislav Momčilović (autor)

Citiraj ovu publikaciju:

Momčilović, Berislav; Alkhatib, A. Hassan; Duerre, A. John; Cooley, M. Alexander; Harris, T. Robert; Lykken, I. Glenn
What do radon daughters tell us about Alzheimer's Disease, Parkinson's Disease, and the smoking habits? Selective distribution of trace elements in the diseased human brain indicate the impairment of Cl- ion membrane transport // Mengen- und Spuren-Elemente. 17 Arbeitstagung 1997 / Anke, Manfred et al/ (ur.).
Leipzig: Verlag Harald Schubert, 1997. str. 574-588 (pozvano predavanje, međunarodna recenzija, cjeloviti rad (in extenso), znanstveni)
Momčilović, B., Alkhatib, A., Duerre, A., Cooley, M., Harris, T. & Lykken, I. (1997) What do radon daughters tell us about Alzheimer's Disease, Parkinson's Disease, and the smoking habits? Selective distribution of trace elements in the diseased human brain indicate the impairment of Cl- ion membrane transport. U: Anke, M. (ur.)Mengen- und Spuren-Elemente. 17 Arbeitstagung 1997.
@article{article, author = {Mom\v{c}ilovi\'{c}, Berislav and Alkhatib, A. Hassan and Duerre, A. John and Cooley, M. Alexander and Harris, T. Robert and Lykken, I. Glenn}, editor = {Anke, M.}, year = {1997}, pages = {574-588}, keywords = {Alzheimer's Disease, Parkinson's Disease, smoking, environmental radon daughters, 210Bi, 210Po, brain proteins, brain lipids, Cl- membrane leakage, low risk radiation injury}, title = {What do radon daughters tell us about Alzheimer's Disease, Parkinson's Disease, and the smoking habits? Selective distribution of trace elements in the diseased human brain indicate the impairment of Cl- ion membrane transport}, keyword = {Alzheimer's Disease, Parkinson's Disease, smoking, environmental radon daughters, 210Bi, 210Po, brain proteins, brain lipids, Cl- membrane leakage, low risk radiation injury}, publisher = {Verlag Harald Schubert}, publisherplace = {Jena, Njema\v{c}ka} }
@article{article, author = {Mom\v{c}ilovi\'{c}, Berislav and Alkhatib, A. Hassan and Duerre, A. John and Cooley, M. Alexander and Harris, T. Robert and Lykken, I. Glenn}, editor = {Anke, M.}, year = {1997}, pages = {574-588}, keywords = {Alzheimer's Disease, Parkinson's Disease, smoking, environmental radon daughters, 210Bi, 210Po, brain proteins, brain lipids, Cl- membrane leakage, low risk radiation injury}, title = {What do radon daughters tell us about Alzheimer's Disease, Parkinson's Disease, and the smoking habits? Selective distribution of trace elements in the diseased human brain indicate the impairment of Cl- ion membrane transport}, keyword = {Alzheimer's Disease, Parkinson's Disease, smoking, environmental radon daughters, 210Bi, 210Po, brain proteins, brain lipids, Cl- membrane leakage, low risk radiation injury}, publisher = {Verlag Harald Schubert}, publisherplace = {Jena, Njema\v{c}ka} }

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