Pregled bibliografske jedinice broj: 197661
Dihydroergotoxine modulation of the GABA-A receptor-associated Cl ionophore in mouse brain
Dihydroergotoxine modulation of the GABA-A receptor-associated Cl ionophore in mouse brain // European journal of pharmacology, 221 (1992), 1; 139-143 doi:10.1016/0014-2999(92)90783-Z (međunarodna recenzija, kratko priopcenje, znanstveni)
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Naslov
Dihydroergotoxine modulation of the GABA-A receptor-associated Cl ionophore in mouse brain
(Dihydroergotoxine modulation of the GABAA receptor-associated Cl− ionophore in mouse brain)
Autori
Tvrdeić, Ante ; Peričić, Danka
Izvornik
European journal of pharmacology (0014-2999) 221
(1992), 1;
139-143
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, kratko priopcenje, znanstveni
Ključne riječi
dihydroergotoxine modulation ; GABA-A ; mouse brain
Sažetak
Dihydroergotoxine non-competitively displaced the binding of t-[3H]butylbicycloorthobenzoate ([3H]TBOB) to crude synaptosomal membranes from the mouse brain (cerebrum minus cortex), and gamma-aminobutyric acid (GABA) (10 microM) enhanced the displacement potency of dihydroergotoxine in a bicuculline-sensitive manner. The same ergot compound prolonged pentobarbital-induced sleeping in mice and diminished the convulsive potency of picrotoxin in the same animal species. The results are indicative of the positive coupling between GABA and dihydroergotoxine.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
POVEZANOST RADA
Ustanove:
Institut "Ruđer Bošković", Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
Uključenost u ostale bibliografske baze podataka::
- Excerpta Medica
- Index Medicus
