Naslov
Morphology of lymphoreticular tissues in mice with reticulosarcoma

Autori
Pavelić, Zlatko ; Boranić, Milivoj ; Pavelić, Krešimir

Izvornik
EXPERIMENTELLE PATHOLOGIE (0014-4908) 15 (1978), 5; 288-295

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
lymphoreticular tissue ; reticulosarcoma ; tumor immunology ; transplantation ; antigenicity ; lymph node ; thymus ; spleen ; reticulohistiocytes ; mouse

Sažetak
The response of murine lymphoreticular tissues to transplantation of a syngenic reticulosarcoma with mild transplantation antigenicity was studied by recording weight changes and histology. The results were compared with those obtained in normal mice and mice challenged with syngenic spleen cells. The tumor induced vigorous histological response in regional lymph nodes and mild response in nonregional lymph nodes and spleen. Mesenteric lymph nodes and thymus did not respond to the tumor. Observed morphological and gravimetrical changes indicated that both regional and nonregional lymph nodes and spleen take part in host immune response to tumor. A possible contamination of tumor tissue ba viruses has been excluded.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA