Pregled bibliografske jedinice broj: 197038
6-amino-6-deoxyascorbic acid induces apoptosis in human tumor cells
6-amino-6-deoxyascorbic acid induces apoptosis in human tumor cells // Journal of cancer research and clinical oncology, 121 (1995), 2; 98-102 doi:10.1007/BF01202220 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 197038 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
6-amino-6-deoxyascorbic acid induces apoptosis in human tumor cells
Autori
Grdiša, Mirica ; Kralj, Marijeta ; Eckert-Maksić, Mirjana ; Maksić, Zvonimir
Izvornik
Journal of cancer research and clinical oncology (0171-5216) 121
(1995), 2;
98-102
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
6-amino-6-deoxyascorbic acid ; apoptosis
Sažetak
6-Amino-6-deoxyascorbic acid was found to inhibit human tumor cell growth. The antitumor effect depends on the tumor type and concentration of the acid. After cell treatment with 6-amino-6-deoxyascorbic acid, drastic morphological changes were found. Although image analysis did not show a difference in p53 and c-myc gene expression, the appearance of chromatin aggregation and DNA fragmentation points to apoptosis or programmed cell death.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
POVEZANOST RADA
Ustanove:
Institut "Ruđer Bošković", Zagreb
Profili:
Mirjana Maksić
(autor)
Zvonimir Maksić
(autor)
Mirica Grdiša
(autor)
Marijeta Kralj
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
