Naslov
Regioselective Hydrolyses of Partially Pivaloylated Mannose Derivatives Catalysed by Esterases from Rabbit Serum
(Pivaloylated Mannose Derivatives Catalysed by Esterases from Rabbit Serum)

Autori
Matanović, Maja ; Petrović Peroković, Vesna ; Matijašič, Ivanka ; Tomić, Srđanka

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, neobjavljeni rad, znanstveni

Skup
XVII. Skup kemičara i kemijskih inžinjera

Mjesto i datum
Osijek, Hrvatska, 10.06.2001. - 13.06.2001

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
mannose derivatives; esterases; rabbit serum

Sažetak
Acid or base catalysed intramolecular migrations of acyls in sugar molecules are well known, and possible mechanism of these transesterifications has been described1. Especially prone to migrations are acetyl groups which migrate spontaneously even in neutral organic solvents2. Intramolecular migrations caused by acid, base catalyze or organic solvents are not usually at pivaloylated carbohydrates. However, it was observed migration of pivaloyl group caused by enzymes present in some mammalian sera and it was previously described in a 14C-marked methyl-2, 6-di-O-pivaloyl-alpha-D-glucopyranoside3. In this work we described spontaneous pivaloyl group migrations in partially pivaloylated mannose, xylose and galactose series of sugars under influence of the reaction media and changeing temperature but without present of enzyme. All reactions were carried out in aqueous buffered solutions at the room and higher (60 C) temperature. 1. T. Horrobin, Ch. H. Tran, D. Crout, J. Chem. Soc., Perkin Trans I (1998) 1069-1080. 2. S. Tomić, Đ. Ljevaković, J. Tomašić, Tetrahedron 49 (1993) 10977-10986. 3. S. Tomić, Lj. Sesartić, J. Tomašić, Comp. Biochem. Physiol. 92B (1989) 681-684.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

POVEZANOST RADA