Pregled bibliografske jedinice broj: 194709
2, 4-Diamino-5-(3, 4, 5-trimethoxybenzyl)-6-arylsulfonyloxypyrimidines and their hydrogenolysis
2, 4-Diamino-5-(3, 4, 5-trimethoxybenzyl)-6-arylsulfonyloxypyrimidines and their hydrogenolysis // Rad Jugoslavenske akademije znanosti i umjetnosti. Razred za matematičke, fizičke i tehničke znanosti. Kemijske znanosti, 5 (1986), 27-32 (podatak o recenziji nije dostupan, članak, znanstveni)
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Naslov
2, 4-Diamino-5-(3, 4, 5-trimethoxybenzyl)-6-arylsulfonyloxypyrimidines and their hydrogenolysis
Autori
Glunčić, Berislav ; Kovačević, Krunoslav
Izvornik
Rad Jugoslavenske akademije znanosti i umjetnosti. Razred za matematičke, fizičke i tehničke znanosti. Kemijske znanosti (0351-8655) 5
(1986);
27-32
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
New 6-hydroxypyrimidine derivatives; New 6-arylsulfonyloxypyrimidine derivatives; Hydrogenolysis by LiALH4 and by hydrogen with Raney Ni
Sažetak
The reaction of ethyl 3, 4, 5-trimethoxybenzylcyanoacetate with guanidine yielded 2, 4-diamino-5-(3, 4, 5-trimethoxybenzyl)-6-hydroxypyrimidine (IV). When this was subjected to the reaction with various arylsulfochlorides in an alkaline medioum it gave a series of 2, 4-diamino-5-(3, 4, 5-trimethoxybenzyl)-6-arylsulfonyloxypyrimidines (V). Hydrogenolysis of compounds V with LiAlH4 and hydrogen with Raney Ni yielded 6-hydroxy compound IV and not trimethoprim in both cases.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
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Uključenost u ostale bibliografske baze podataka::
- Chemical Abstracts
