Pregled bibliografske jedinice broj: 192525
Passive avoidance deficit in rats with disruption of cortical cholinergic input can be improved by lecithin or arecoline, but not by piracetam
Passive avoidance deficit in rats with disruption of cortical cholinergic input can be improved by lecithin or arecoline, but not by piracetam // Iugoslavica physiologica et pharmacologica acta, 24 (1988), 2; 145-153 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 192525 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Passive avoidance deficit in rats with disruption
of cortical cholinergic input can be improved by
lecithin or arecoline, but not by piracetam
Autori
Simonić, Ante ; Župan, Gordana
Izvornik
Iugoslavica physiologica et pharmacologica acta (0021-3225) 24
(1988), 2;
145-153
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
nucleus basalis lesion ; passive avoidance ; lecithin ; arecoline ; piracetam ; rat
Sažetak
Intact cholinergic system is a prerequisite to unimpaired performance in learning and memory tasks. Bilateral electrolytic lesions of the nucleus basalis (NB) equivalent reduce the passive avoidance in the rat. The effect of intraperitoneally injected lecithin (3.2 x 10-4 mol.kg-1), arecoline (6.4 x 10-6 mol.kg-1), or piracetam (1.4 x 10-2 mol.kg-1) alone or in combination with before mentioned cholinomimetics on the passive avoidance in NB lesioned rats was examined. It was found that lecithin and arecoline alone or in combination with piracetam improved the avoidance acquisition in NB lesioned rats, while piracetam was uneffective.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
POVEZANOST RADA
Ustanove:
Medicinski fakultet, Rijeka
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
