Naslov
Extended-spectrum-beta-lactamase-producing Enterobacteriaceae in Yaounde, Cameroon

Autori
Gangoue-Pieboji, Joseph ; Bedenić, Branka ; Koulla-Shiro, Sinata ; Rendegger, Corinne ; Adiogo, Dieudonne ; Ngassam, Pierre ; Ndumbe, Peter ; Hachler, Herbert

Izvornik
Journal of clinical microbiology (0095-1137) 43 (2005), 7; 3273-3277

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
antimicrobial agents; Cameroon; Enterobacteriaceae; extended-spectrum beta-lactamases; resistance; SHV-12; Yaounde

Sažetak
Organism producing extended-specrum beta-lactamases (ESBLs) have been reported in many countries, but there is no information on the prevalence of ESBL-producing members of the family Enterobacteriaceae in Cameroon. A total of 259 strains of Enterobacteriaceae were isolated between 1995 and 1998 from patients at the Yaounde Central Hospital in Cameroon. Thirty-one (12%) of these Enterobacteriaceae strains were shown to be positive by the double-disk sinergy test, suggesting the presence of ESBLs. The beta-lactamases produced by the 12 transconjugants turned out to be SHV-12 by DNA sequencing. Therefore, the ESBL SHV-12 is described for the first time in Cameroon.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA