Estrogen receptor (ER) in breast cancer tissue of premenopausal patients: are some ER- findings false due to down-regulation?

Kurbel, Sven; Kovačić, Damir; Kristek, Jozo; Šišljagić, Vladimir; Mihaljević, Ivan

doi:10.1016/j.mehy.2004.12.003

Pregled bibliografske jedinice broj: 191896

Estrogen receptor (ER) in breast cancer tissue of premenopausal patients: are some ER- findings false due to down-regulation?

Kurbel, Sven; Kovačić, Damir; Kristek, Jozo; Šišljagić, Vladimir; Mihaljević, Ivan

Estrogen receptor (ER) in breast cancer tissue of premenopausal patients: are some ER- findings false due to down-regulation? // Medical hypotheses, 64 (2005), 5; 1069-1070 doi:10.1016/j.mehy.2004.12.003 (podatak o recenziji nije dostupan, pismo, stručni)

CROSBI ID: 191896 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Estrogen receptor (ER) in breast cancer tissue of premenopausal patients: are some ER- findings false due to down-regulation?

Autori
Kurbel, Sven ; Kovačić, Damir ; Kristek, Jozo ; Šišljagić, Vladimir ; Mihaljević, Ivan

Izvornik
Medical hypotheses (0306-9877) 64 (2005), 5; 1069-1070

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pismo, stručni

Ključne riječi
breast neoplasms ; estrogen receptors ; down-regulation

Sažetak
Estrogen receptor (ER) and progesterone receptor (PR) status at the time of breast carcinoma surgery is used as a marker of both prognosis and hormone dependency to guide adjuvant therapy [1]. This approach is based on the accumulated knowledge that the presence of estrogen and/or progesterone receptors typically suggests slower-growing tumors, amenable to hormonal manipulation [2]. In most clinical studies and therapy recommendations, breast cancer is considered hormone dependent if at least one receptor type is present in the tumor tissue.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA

Projekti:
0127051

Ustanove:
Klinički bolnički centar Osijek

Profili:

Ivan Mihaljević (autor)