Naslov
Trisomy and tetrasomy of the long arm of chromosome 1 in a direct preparation of human endometrial adenocarcinoma
(Trisomy and tetrasomy of the long arm of chromosome 1 in a direct praparation of human endometrial adenocarcinoma)

Autori
Horgas, Goran ; Grubišić, Goran ; Spaventi, Šime

Izvornik
Cancer genetics and cytogenetics (0165-4608) 35 (1988), 2; 269-272

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
chromosomes human pair 1; trisomy

Sažetak
Chromosome banding analysis was performed on an endometrial adenocarcinoma. A minimal variety in the chromosome number and morphology was found. All analyzed pseudodiploid and aneuploid carcinoma cells had two chromosomes 1 of normal morphology and the presence of a marker of markers derived from chromosome 1. Tetrasomy of the long arm of chromosome 1 was found in 12 of 19 cells analyzed, accompanied by trisomy of the long arm of chromosome 1 in the rest of the cells. No other common chromosome marker was observed. Previously published data and our results suggest that trisomy and tetrasomy of the long arm of chromosome 1 may represent a specific karyotypic change in subtypes of endometrial adenocarcinoma.

Izvorni jezik
Engleski

POVEZANOST RADA