Naslov
The cytology smears of the healthy human parathyroid gland

Autori
Banek, Tomislav ; Banek, Ljerka ; Pezerović-Panijan, Ružica ; Škreb, Franjo

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstract book of the 29th European congress of cytology / - Prag : Univerzita Karlova v Praze Nakladatelstvi Karolinum, 2003, 334-334

Skup
29th European congress of cytology

Mjesto i datum
Prag, Češka Republika, 05.10.2003. - 08.10.2003

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
parathyroid gland; healthy gland; cytology; cytological smear

Sažetak
On histological sections, the parenchyma of healthy human parathyroid glands contains dark and light chief cells as well as oxyphilic cells. The morphology of these cells, in cytological smears had not yet been described. The aim of the study was to compare the morphology of these cells in cytological smears with their structure on histological sections and to give criteria for their recognition in the smears. In the survey, healthy human parathyroid glands of 47 patients (27 females and 20 males) were analyzed. This material was obtained during surgical operation of the thyroid gland, with which parathyroids were closely anatomically associated and sometimes involuntary removed. The tissue that was supposed to correspond to parathyroids was divided into 2 pieces. The first on was fixed in Gendre and processed by standard methods for a histological light microscopic analysis. From the second piece, the smears were made by the imprint method, air dried and stained by MGG. The results of this investigation show that in the cytological smears (as well as on histological sections) predominate dark and light chief cells. The dark chief cells, which are more numerous than light chief cells, have smaller nucleus, with dark, dense chromatin and without visible nucleolus( Fig.1.). Light chief cells have bigger nucleus, with lighter, looser chromatin and with visible one or two nucleoli. Their cytoplasm is poor defined, grey-blue in colour, often vaculated (Fig.2.). In the dark oxyphilic cells, the nuclei are smaller, with darker chromatin and without a visible nucleolus ( Fig.3.). Light oxyphilic cells have larger nucleus, with rare chromatin and a visible nucleolus. Their cytoplasm is dense, gray-rose and well defined (Fig.4.). Identification of parenchymal cell subtypes of human parathyroid glands and determination of their participation in the smears, may give an insight into functional state of this gland and its possible disturbance in pathological processes.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA