Naslov
Immunohistochemical and stereological study of neuroendocrine cells in human antrum during the perinatal period

Autori
Bojan, Rode ; Lacković, Gordana ; Pirkić, Ahmed

Izvornik
The International journal of developmental biology (0214-6282) 35 (1991); 303-309

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
human antrum ; perinatal period ; neuroendokrine cells ; stereology ; immunohistochemistry

Sažetak
A correlative immunohistochemical and stereological study of neuroendocrine cells (NEC) was carried out in the antrum of twenty human fetuses with gestational ages from 18 to 42 weeks and two specimens postnatally. NSE as a common marker of neurons and NEC, as well as gastrin (G-) and somatostatin (D-) immunoreactivecells served for evaluation of volume density, which proved to be the most convient method for quantitative analysis of NEC. It was observed that a considerable frequency of >N>EC appeared at 23-24 gestational weeks and coincided with the adult pattern of intramural inervation. The maximal quantitative difference of NEC was noted between 6- and 8-week specimens postnatally, e.g. 9% to 22% of G-cells, respectivelly. Observations obtained by NSE and S-100 protein were also demonstrated in lymphoid cells of gut associated and mesenteric lymphoid tissue.

Izvorni jezik
Engleski

POVEZANOST RADA