Naslov
Influence of industrial exposure and smoking habit on sensitization of the respiratory system

Autori
Kanceljak, Božica ; Macan, Jelena ; Milković-Kraus, Sanja ; Plavec, Davor

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Allergy / Lee, T.H. ; Frew, A.J. - Kopenhagen : Munksgaard, 1998, 35-35

Skup
The Annual Meeting of the European Academy of Allergology and Clinical Immunology, EAACI '98

Mjesto i datum
Birmingham, Ujedinjeno Kraljevstvo, 21.06.1998. - 26.06.1998

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Sažetak
Sensitization of the respiratory system and skin was studied in 166 women (mean age 28.06.4) and 185 men (mean age 26.3 5.4) during preemployment examination. In subjects previously employed in different industrial plants for one year and more (IND+) there were 61/166 (36.7%) women and 70/185 (37.8%) men. There were 106/185 (57.3%) smokers among men and 84/166 (50.6%) among women. Total IgE was determined by PRIST test (Pharmacia Diagnostic, Upsala) and analysed as geometric mean (GM). Prick test (PT) was done with common inhalatory allergens (Institute of Immunology, Zagreb) and urtica mean diameter (D+d/2) 3 mm or more was considered a positive reaction (PT+). Patch test (ET) was done with European standard series (ALK-Epipharm, Linz) and erythema and/or oedema with vesicles was considered a positive reaction (ET+). There was a higher prevalence of PT+ among IND+ women, than in IND - women (32.8%: 21.0%, p < 0.05). Such difference was not found in men. Prevalence of ET+ was similar in IND+ and IND - women (29.5%: 31.4%, n.s.) and in IND+ and IND - men (21.4%: 16.5%, n.s.). Between smokers and nonsmokers there were no differences in the prevalence of either PT+ subjects in women (22.6%: 28.1%, n.s.) and men (41.5%: 34.2%, n.s.), or in ET+ subjects in women (35.7%: 25.6%, n.s.) and men (17.9%: 19.0%, n.s.). Between IND+ and IND - subjects there were no differences in total IgE either in women (42.7 kU/L: 44.2 kU/L, n.s.), or in men (75.7 kU/L: 70.3 kU/L, n.s.). Our results indicate that preexisting industrial exposure has an influence on sensitization of the respiratory system in women, but not on contact sensitization in either women or men. We conclude that it is important to detect atopic workers during preemployment and periodic examinations for risk industrial occupations.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA