Naslov
Lymphocyte subpopulations in the blood and cerebrospinal fluid of multiple sclerosis patients in active disease

Autori
Rukavina, Daniel ; Sepčić, Juraj ; Dorić, Miljenko ; Ledić, Petar ; Zaputović, Luka ; Eberhardt, Predrag

Izvornik
Acta neurologica scandinavica (0001-6314) 69 (1984); 181-185

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
T cells ; B cells ; blood ; cerebrospinal fluid ; multiple sclerosis

Sažetak
Lymphocyte subpopulations (total T cells, active T cells and B cells) were simultaneously analyzed in peripheral blood and CSF of MS patients. All patients were in active disease, 3 to 4 weeks after first signs of disease activation appeared. Per cent levels and absolute numbers of examined lymphocyte subpopulations in the blood of MS patients were significantly lower than in healthy controls. In MS, the level of active T lymphocytes was lower in CSF than in peripheral blood. The results support our earlier observations relating to the role of active T lymphocytes in the clinical course of disease.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA