Naslov
Morphological changes in the organs of gilts induced with low-dose atrazine

Autori
Ćurić, Stipica ; Gojmerac, Tihomira ; Žurić, Marijan

Izvornik
Veterinarski arhiv (0372-5480) 69 (1999), 3; 135-148

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
atrazine; intoxication; morphological changes; gilts; pig

Sažetak
In this study we have investigated morphological changes in organs of gilts treated with low doses of atrazine, and s-triazine herbicide. Gilts (cross-bred Swedish and German Landrace) received 2 mg atrazine/kg body mass in feed during 19 days of the oestrus cycle. The final day of treatment corresponded to day -3 of the onset of the next expected oestrus. Macroscopically, in treated gilts we have found cystic ovarian degeneration. Histopathologically, mild parenchymatous degeneration of liver was noted, with mild chronic interstitial hepatitis and stenosis, as well as irregular shape of bile ducts. In kidneys we found sub-acute glomerulitis with atrophy of single glomerules and parenchymatous degeneration with desquamation epithelial cells of some tubules and appearance of proteinaceous casts in their lumen. A cereal degeneration of a small number of muscular fibres was noted in the myocard. Multiple follicular cysts and persisting corpus luteum existed in ovaries, while the uterus was in a resting period (dioestrus). Additionally, lymphoid depletion in lymphoid follicles of lymph nodes and spleen was observed, as well as infiltration of lymphocytes in interstitial tissue of liver and kidneys, together with infiltration of eosinophils in liver and lymph nodes.

Izvorni jezik
Engleski

Znanstvena područja
Veterinarska medicina

POVEZANOST RADA