Pregled bibliografske jedinice broj: 184622
THYROID DYSFUNCTION AND BONE MINERAL DENSITY IN THE EARLY POSTMENOPAUSE
THYROID DYSFUNCTION AND BONE MINERAL DENSITY IN THE EARLY POSTMENOPAUSE // EULAR 2004 Germany, Berlin 9-12 June 2004
Berlin, Njemačka, 2004. (poster, međunarodna recenzija, sažetak, stručni)
CROSBI ID: 184622 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
THYROID DYSFUNCTION AND BONE MINERAL DENSITY IN THE EARLY POSTMENOPAUSE
Autori
Jelčić, Jozo ; Kušec, Vesna ; Kifer, Tomislav Delija, Alboran ; Koršić, Mirko
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni
Skup
EULAR 2004 Germany, Berlin 9-12 June 2004
Mjesto i datum
Berlin, Njemačka, 09.06.2004. - 12.06.2004
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
BMD; postemenopauza; disfunkcija tirodne žlijezde
(bone density in postmenopausal women; thyroid dysfunction)
Sažetak
Background: The most common form of primary osteoporosis occurrs in the postmenopause with most of the bone mass lost in the early postmenopause. Hyperthyroidism is one of the major risk factors for secondary osteoporosis, due to increased bone turnover and accelerated bone loss. Objectives: The aim of this study was to investigate bone density in postmenopausal women with thyroid dysfunction. Methods: This retrospective analysis comprised 42 hyperthyroid, 92 hypothyroid and 562 euthyroid patients aged 40-85 years. Bone mineral density (BMD) was measured at the lumbar spine and femoral neck by dual X-ray absorptiometry. Results: Patients with hypothyroidism were significantly younger than those without thyroid disorder (59.7 yr. vs. 62.1 yr.) and had significantly higher BMD in the lumbar spine and hip. Analysis of data for age groups revealed that the statistically significant difference (p<0.005) for the lumbar spine and hip BMD was found only for the 51-55 year old patients. No difference existed between the other two pairs of patient groups, i.e. the euthyroid and hyperthyroid and the hypothyroid and the hyperthyroid. There was no difference in incidence of osteopenia (T-score <-1) and osteoporosis (T-score <-2.5) between the three patient groups. Conclusion: These results suggest a protective effect of hypothyroidism on the skeleton in the early postmenopause probably by decelerated bone turnover and bone loss.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
