Naslov
LONG-TERM METABOLIC AND ENDOCRINE ACTIVITY CHANGES IN RESPONSE TO CLENBUTEROL IN MATURE FEMALE PIGS

Autori
Gojmerac, Tihomira ; Koršić, Mirko ; Tomašić, Ana ; Vinković, Bara

Izvornik
Toxicology letters (0378-4274) 144 (2003); 82-82

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, kongresno priopcenje, znanstveni

Ključne riječi
klenbuterol; promotor rasta; endokrina aktivnost; metabolizam; svinje
(clenbuterol; growth-promotor; endocrine activity; metabolism; pigs)

Sažetak
In present study, the effect of intravenously repeated administration of clenbuterol in a growth-promotiong dose on the metabolic and endocrine status of mature female pigs was evaluated on the basis of biochemical findings.Serum 17beta-estradiol and progesterone concentrantion and serum insulin, nonesterified fatty acid and glucose concentration were measured after long-term administration of clenbuterol to mature female pigs.On the basis of the data obtained, we suggest that long-term administration of clenbuterol in growth-promoting dose to female pigs provoked only subtle metabolic and endocrine activity changes, indicating down-regulation of the specific beta2-adrenergic receptors in target tissues.

Izvorni jezik
Engleski

Znanstvena područja
Veterinarska medicina

POVEZANOST RADA