Naslov
Value of aspiration cytology and intraoperative imprints in the diagnosis of medullary carcinoma

Autori
Halbauer, Mira ; Tomić-Brzac, Hrvojka ; Šarčević, Božena ; Jakić, J ; Radetić, Miljenko ; Medvedec, Mario ; Dodig, Damir Dodig

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Book of Abstract, Fourth International Congress of the Croatian Society of Nuclear Meidicine / Božidar Kasal - Zagreb : Medicinska naklada, 2002

Skup
Fourth International Congress of the Croatian Society of Nuclear Meidicine

Mjesto i datum
Opatija, Hrvatska, 12.05.2002. - 15.05.2002

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Nije recenziran

Ključne riječi
aspiration cytology; intraoperative imprints; medullary thyroid carcinoma

Sažetak
The growth of medullary carcinoma of the thyroid (MCT) is very slow, but progressive, requiring an easy and reliable diagnostic method in the early stage of the disease. The variable cytologic features of MCT which reflect the histology of different subtypes of this neoplasm, may produce diagnostic problems. The aim of our study was to correlate preoperative and intraoperative cytologic diagnoses of MCT with pathohistology, to assess the value of both techniques. During an 8-year period, 108 fine needle aspiration biopsies under ultrasound guidance were performed in 43 patients (30 F and 13 M). In 3 patients tumor had familial occurrence. Preoperative cytologic diagnosis was based on a specific cytologic morphology of MCT in fine needle aspirates. In most patients, additional use of cytochemical method with silver nitrate stain resulted in positive argyrophilia. In 40/43 patients, cytologic diagnosis of MCT was consistent with pathohistology ; in most patients cytology pointed to papillary carcinoma, and in one patient to follicular carcinoma. However, intraoperative imprint diagnoses were positive fot MCT in all our patients. Accordingly, cytology was concluded to be an excellent method for preoperative and intraoperative diagnosis of MCT. Therefore, we strongly recommend combined use of both methods in the early diagnosis of disease.

Izvorni jezik
Engleski

POVEZANOST RADA