Naslov
Pancreatic Neuroendocrine Tumor presenting with carcinoid syndrome : Case report

Autori
Berković, Maja ; Zjačić-Rotkvić, Vanja ; Goldoni Vesna ; Hrabar, Davor ; Karapandža, Nikola ;

Izvornik
Acta Clinica Croatica (0353-9466) 42 (2003), 4; 347-350

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, prikaz, znanstveni

Ključne riječi
Neuroendocrine tumors; diagnosis; Pancreatic neoplasms; diagnosis; Pancreatic neoplasms; drug therapy; Carcinoid tumor; diagnosis; Carcinoid tumnor; drug therapy; Case report
(Neuroendocrine tumors; diagnosis; Pancreatic neoplasm; diagnosis; Pancreatic neoplasms; drug therapy; Carcinoid tumor; diagnosis; Carcinoid tumor; drug therapy; Case report)

Sažetak
Carcinoid is the most common neuroendocrine tumor. It is primarily localized in the ileum and the appendix, whereas other localizations are rare. Only a small number of the carcinoids present with carcinoid syndrome, (flushing.diarrhea), usually after tumor has already metastasized. A case of carcinoid tumor of uncommon localization is reported. A 54-year-old male patient presented for evaluation because of weight loss, flushing and diarrhea. Laboratory value of 5-HIAA was 775.5 mmol/l (normal values up to 72.8) and the pancreatic tumor marker CA l9-9 was increased. Ultrasonografic and magnetic resonance findings localized the tumor in the prepapillary pancreatic region and visualized the spread to the liver. The diagnosis was confirmed by pathohistologic evaluation of a liver biopsy specimen. The patient was treated with Sandostatin (octreotide analog), which led to significant relief of the symptoms, although control 5-HIAA values were not reduced.

Izvorni jezik
Engleski

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