Naslov
Improving of biomonitoring strategy trough collaboration of clinical cytogenetics with genetical toxicology

Autori
Hitrec, Vlasta ; Fučić, Aleksandra ; Lasan, Ružica

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Health Insurance in Transition:Biotechnology and Public Health: Expectations, Gains and Costs / - Zagreb, 2002

Skup
5th International Conference Health Insurance in Transition ; Biotechnology and Public Health: Expectations, Gains and Costs

Mjesto i datum
Zagreb, Hrvatska, 26-28. 09

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Clinical cytogenetics; Genetical toxicology

Sažetak
For the last few decades genetical toxicology has been relying on unstable biomarkers such as chromosome aberrations, micronucleus frequency and sister chromated exchange frequency as indicator of genome damage after exsposure to mutagenic and carcinogenic agents. Although the basic aim of genetical toxicology is to evaluate the risk of cancer development, stable aberrations (translocations, inversions, deletions) critical in carcinogenesis have not been detected due to lack of sutible methods. The collaboration between clinical cytogenetics and genetical toxicology confirms mimportance of translocations.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA