Naslov
Does CO2 measurement predict outcome of sepsis?

Autori
Pilaš, Vladimir ; Čubrilo-Turek, Mirjana ; Čala, Krešimir ; Vranjković, Slavo ; Nikša, Vučić

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Neurologia Croatica vol. 53, Suppl. 2 / - , 2004

Skup
11th Symposium on Intensive Care Medicine

Mjesto i datum
Brijuni, Hrvatska, 21.06.2004. - 23.06.2004

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Domaća recenzija

Ključne riječi
CO2; sepis; shock

Sažetak
Tissue hypoxia is a leading sign of septic shock. The oxygen uptake (VO2) is absolutely or relatively low. Production and elimination of CO2 (VCO2) is also impaired. We assumed that measurement of this phenomenon may be useful for evaluation of therapy success. We followed VCO2 in 18 adult patients with conventional criteria of septic shock during hemodynamic resuscitation. Resuscitation was guided after variables obtained by invasive hemodynamic monitoring (Swan-Ganz catheter). Colloid and cristalloid fluids as well as inotropes and vasopressors were administered when necessary. Initial findings indicated hypovolemic-hyperkinetic status with decreased VO2. VCO2 was measured by expired gas analysis via metabolic monitor. Initial findings after 3th and 6th. hour of therapy were taken into analysis. In seven survived patients baseline values of VCO2 were increased as compared in those who died (194 &plusmn ; ; 21 vs. 176 &plusmn ; ; 28, p<0.05 ml/min). VCO2 further increased in survivors, particularly after the 6th hour. In nonsurvivors, VCO2 did not change significantly despite improved hemodynamic profile. We consider that results of this preliminary study allow conclusion that simple measurement of VCO2 may provide useful information on severity of metabolic disorder in septic shock. The efficiency of resuscitation may be evaluated by this test.

Izvorni jezik
Engleski

Napomena
01/0112910

POVEZANOST RADA