Pregled bibliografske jedinice broj: 173041
Symptoms prevalence during chemotherapy in elderly patients (pts) with colorectal cancer (CRC)
Symptoms prevalence during chemotherapy in elderly patients (pts) with colorectal cancer (CRC) // Gut, An International Journal of Gastroenterology and Hepatology / T. Rosch (ur.).
London : Delhi: Georg Thieme Verlag, 2004. (poster, međunarodna recenzija, sažetak, stručni)
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Naslov
Symptoms prevalence during chemotherapy in elderly patients (pts) with colorectal cancer (CRC)
Autori
Željka, Bagić ; Renata, Dobrila-Dintinjana ; Iris, Djipalo ; Marijan, Dintinjana ; Davor, Štimac
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni
Izvornik
Gut, An International Journal of Gastroenterology and Hepatology
/ T. Rosch - London : Delhi : Georg Thieme Verlag, 2004
Skup
12th UEGW Prague 2004
Mjesto i datum
Prag, Češka Republika, 25.10.2004. - 30.10.2004
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
symptoms prevalence; chemotherapy; elderly patients; colorectal cancer
Sažetak
Introduction : Incidence of CRC is increasing, especially in elderly. Elderly pts are suffering from commorbid diseases (cardiovascular, respiratory, diabetes, etc.), they are using more medications and can be frail. Aim : To establish does chemotherapy cause different symptoms in elderly pts versus younger pts with CRC. Patient and methods : 388 pts with CRC were cured in our hospital from 1997-2003. We took age 70 as borderline. There was 162 elderly pts and 226 younger. Pts were treated with standard chemotherapeutic protocols (Mayo Clinic, Roswell Park, Folfiri, Capecitabine). In the group of elderly we adjusted medication doses according to commorbid diseases and frailty. Intensitiy of symptoms was reviewed according to WHO grading before and after first and second chemotherapeutic protocol. Results : In elderly group (75, 37 years), 27, 2% pts developed side effects (2, 3 pro pts). The most common were fatigue (37, 3%), emesis (19, 6%) and neutropenia (17, 7%). In younger pts (55, 75 years) side effects had 25, 7% pts (3, 1 pro pts) and fatigue was also the most common symptom (31, 7%). Conclusions : There was no difference between type and frequency of chemotherapy side effects according to age. The average number of side effects is higher in young pts (3, 1 versus 2, 3) ; but elderly had more serious neutropenia than younger. There was no need to stop chemotherapy in elderly because of the side effects. Taking in consideration commorbid diseases and pts frailty application of chemotherapy in elderly is saame safe and useful as in the younger pts.
Izvorni jezik
Engleski
Znanstvena područja
Javno zdravstvo i zdravstvena zaštita
