Naslov
Risk factors for an unfavorable outcome in juvenile idiopathic arthritis: retrospective study in Croatia.

Autori
Tambić Bukovac, Lana, Prohić, Avdo, Jelušić, Marija, Malčić, Ivan, Potočki, K

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Annals of the Rheumatic Diseases 63(Suppl 1): / - , 2004

Skup
Annual European Congress of Rheumatology, EULAR 2004, Berlin

Mjesto i datum
Berlin, Njemačka, 12.06.2003. - 15.06.2003

Vrsta sudjelovanja
Ostalo

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
JIA; prognostic; factors

Sažetak
The aim of our study was to identify risk factors for an unfavorable outcome in children with juvenile idopathic arthritis (JIA). Patients and methods: One hundred ninety-eight children with JIA, first admitted to the Department of Paediatric Rheumatology, University Hospital Zagreb, Croatia, between 1990 and 1995 were examined after 7 to 12 years (median 8.4) of disease duration. Clinical examination, laboratory variables (ESR, platelets, hemoglobin, ANA, HLA-B27 and radiographs of affeceted joints were obtained. Results: At follow up, 119 patients (60, 1%) were in remission, 47 (23, 7%) had developed joint erosions, and 32 (16, 2%) had different functional disabilities, which required orthopedic prostheses or in some cases operation. The remission rate was higher in the patients with persistent oligoarticular than in those with extended oligoarticular and RF positive polyarticular JIA. Conclusion: In our study early risk factors for an unfavorable outcome were young age at onset, female sex, symmetric arthritis (polyarthrtitis), early hip joint involvement, early joint erosions, elevated ESR, positive RF and HLA-B27. The presence of uveitis in oligoarticular onset JIA didn’ t show like unfavorable prognostic factor, like was suggested in some studies

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA