Naslov
Association of the congenital anomalies

Autori
Bonevski, Aleksandra ; Stepan-Giljević, Jasminka ; Nakić, Melita ; Ćepulić, Mladen ; Petković, Iskra ; Čižmić, Ante

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Mjesto i datum
,

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
Congenital anomalies; Wilm's tumour

Sažetak
Objectives. We tried to evaluate how often is the Wilm's tumour associated with congenital anomalies and some other diseases in the patients treated at our department. Methods: The association of Wilm's tumour and congenital anomalies is explained by the closeness if the gene responsable for Wilm's tumour and following anomalies: aniridia, hemihypertrophy (beckwith-Wiedemann sy), cryptorchidism, hypospadias and other genital malformations. Also, it occurs in conjunction with some diseases, such as neurofibromatosis. Cytogenetic analysis has identified the genes responsible for the appearance of Wilm's tumour. The 2 of them are placed at the 11th chromosome, and one is placed at the 16th chromosome. From 1994-2002. we have treated 43 patients with Wilm's tumour. Most of them were between 2 and 6 years of age. 13 od them had some anomaly, mostly genitourinary (7 of them), none have aniridia, and 2 of them had bilateral Wilm's. We had 1 patient who has been presented with hemihypertrophia and 3 patients who has had genitourinary anomalies, mostly criptorchidism in the nearest family. Results. 30.2% (13) of the patients treated of Wilm's tumour has had some congenital anomaly associated with the tumour. Conclusion. Approximately one third of the patients treated of wilm's tumour has had some congenital anomaly and therefore every child who has such anomaly shoul be examined for the Wilm's tumour, so the ultrasound (US) screening of the abdomen is recommendedd to be done.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA