Pregled bibliografske jedinice broj: 170275
Transcription factors from Ikaros gene family in human malignancies
Transcription factors from Ikaros gene family in human malignancies // 12th International Congress of Immunology and 4th Annual Conference of FOCIS / IUIS, FOCIS (ur.).
Montréal: -, 2004. (poster, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 170275 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Transcription factors from Ikaros gene family in human malignancies
Autori
Antica, Mariastefania ; Beluzic Robert ; Tomljenović, Andrea ; Dzebro, Sonja ; Dominis, Marija
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
12th International Congress of Immunology and 4th Annual Conference of FOCIS
/ IUIS, FOCIS - Montréal, 2004
Skup
12th International Congress of Immunology and 4th Annual Conference of FOCIS
Mjesto i datum
Montréal, Kanada, 18.06.2004. - 23.06.2004
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
Ikaros; transcription factors; lymphoid
Sažetak
Transcription factors from the Ikaros family, Aiolos and Helios, play an essential role in the commitment of hematopoietic progenitors into the lymphoid lineage as well as in the choice of effector functions at later stages of development. Gene targeting studies in mice and also studies of cell populations from leukemic patients indicate that Ikaros, Aiolos and Helios might be involved in leukemogenesis. Therefore we analyzed Aiolos and Helios expression in 8 hematological cell lines, and leukemic cells from 17 patients with morbus Hodgkin’ s and 24 patients with non-Hodgkin’ s lymphoma. Our results show that the pattern of expression of Aiolos and Helios is not homogeneous among different subsets of leukemia.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
