Pregled bibliografske jedinice broj: 168518
Antimicrobial Prescribing in Hospitalized Pediatric patients: ACross-National Comaprison between Marburg (Germany) and Rijeka (Croatia)
Antimicrobial Prescribing in Hospitalized Pediatric patients: ACross-National Comaprison between Marburg (Germany) and Rijeka (Croatia) // Pharmacoepidemiology and Drug Safety 2004 ; 13(Suppl.1)S64-S65 / Mann, Ronald D (ur.).
Glasgow: Wiley Interscience, 2004. str. S64-S65 (poster, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 168518 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Antimicrobial Prescribing in Hospitalized Pediatric patients: ACross-National Comaprison between Marburg (Germany) and Rijeka (Croatia)
(Antimicrobial Prescribing in Hospitalized Pediatric patients: ACross-National Comaprison)
Autori
Ufer, Mike ; Radošević, Nives ; Vogt, Anne ; Palčevski, Goran ; Francetić, Igor ; Seyberth, Hanns J ; Ahel, Vladimir ; Vlahović-Palčevski, Vera
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Pharmacoepidemiology and Drug Safety 2004 ; 13(Suppl.1)S64-S65
/ Mann, Ronald D - Glasgow : Wiley Interscience, 2004, S64-S65
Skup
20th International Conference on Pharmacoepidemiology & Therapeutic Risk Management
Mjesto i datum
Bordeaux, Francuska, 22.08.2004. - 25.08.2004
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
antimicrobial drugs; children; pediatrics; inpatient; drug utilization
Sažetak
Background: Antibiotics represent the most commonly used drugs in the pharmacological treatment of children and adolescents. However, knowledge about patterns of antibiotic utilisation in children remains sparse throughout Europe. Objectives: To compare the utilisation of systemic antibiotics in the pediatric inpatient setting between two university hospitals in Germany and Croatia. Methods: We analysed antibiotic drug treatment among inpatients 18 years that were consecutively admitted to the University hospitals of Marburg (Germany) and Rijeka (Croatia) as from January 2003. In each center, 300 incident users of systemic antibiotics were included. Data retrieval was based on information from the medical charts by means of a standardized questionnaire addressing indication, symptoms, and treatment characteristics. Antibiotic utilisation was evaluated with respect to drug choice, treatment duration, and administered dose. Each drug was classified to the 5th level of the Anatomical Therapeutic Chemical (ATC) classification system. We also assessed the extent of antibiotic treatment verified by pathogen identification or susceptibility test. Results: In both centers, more than ⅓ of patients were younger than 1 year and an even gender distribution was observed. In Marburg, we identified 21 different antibiotic generics as opposed to 30 in Rijeka. Ampicillin (J01CA01) and cefuroxime (J01DA06) were most frequently used in Marburg each drug constituting about ⅓ of all antibiotic courses. In Rijeka, ceftriaxone (J01DA13) was most commonly used accounting for more than of all antibiotic courses, whereas it was seldomly prescribed in Marburg. In both centers, pneumonia was the most common indication. More than 75 % of antibiotic treatment courses were initiated empirically based on clinical symptoms without any pathogen identification or susceptibility test. Conclusions: Despite similar study population characteristics, a greatly different antibiotic utilisation profile was observed in Marburg (Germany) and Rijeka (Croatia). A further evaluation of drug choice determinants and of the quality of prescribing are warranted.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
