Naslov
Microwave assisted IMDAF reaction: Microwave irradiation applied with success to cycloaddition reaction of N-Propargyl-N-p-tolyl-N-2-furfurylamines.

Autori
Mance, Ana Dunja ; Jakopčić, Krešimir

Izvornik
Molecular diversity (1381-1991) 9 (2005); 229-232

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
MAOS; IMDAF; epoxyisoindoline; [4+2]cycloaddition; alkynylarylfurfurylamine.

Sažetak
The new tertiary furfurylamine with triple bond as a dienophylic part i. e. N-(5-methyl-2-furfuryl)-N-prop-2-ynyl-p-toluidine (1) was prepared and the intramolecular Diels-Alder reaction of the amine (1) was performed under microwave irradiation conditions and by heating a benzene solution of the amine under nitrogen. Comparing the results of the usual thermal and the MAOS reaction, we confirmed our expectations that MAOS could promote the outcome of IMDA reaction of the suitably N-substituted tertiary 2-furfuryl-amines. In the present example, N-p-tolyl-5-methyl-5, 7a-dihydro-5, 7a-epoxyisoindoline was obtained in much better yield and of higher purity.

Izvorni jezik
Engleski

Znanstvena područja
Kemijsko inženjerstvo

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