Naslov
Primary non-hodgkin lymphoma of the humerus following traumatic injury:case report

Autori
Stemberga, Valter ; Dobi-Babić, Renata ; Bosnar, Alan ; Cuculić, Dražen ; Fučkar, Dora ; Štifter, Sanja ; Kušec, Rajko ; Marušić-Vrsalović, Maruška ; Jonjić, Nives

Izvornik
Hematological oncology (0278-0232) 21 (2003), 3; 109-114

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
bone lymphoma; prognosis; trauma-related tumour

Sažetak
A case of primary non-Hodgkin lymphoma of the right humerus which occurred in a 21-year-old male patient after an impact to the right shoulder in a car accident in July 1983 is described. Seventeen years after the injury, due to a civil lawsuit, the biopsy material was revised. Immunohistochemical analysis showed CD20 and CD79a positivity on large pleomorphic cells, while small reactive lymphocytes were CD3, Bcl-2 and CD20 positive. Molecular analysis carried out with PCR revealed a monoclonal B-lymphocyte population. The diagnosis of diffuse large peripheral B cell lymphoma of the bone was confirmed. The present case concurs with the literature on primary bone lymphoma, in which the diagnostic problem, trauma-related presentation and an excellent prognosis of malignant tumour are emphasized.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA