Pregled bibliografske jedinice broj: 16289
Properties of recombinant alpha (1) beta (2) gamma (2s) form of the rat GABA-A receptor expressed in the 293 human embryonic kidney cell line
Properties of recombinant alpha (1) beta (2) gamma (2s) form of the rat GABA-A receptor expressed in the 293 human embryonic kidney cell line // XXIInd CINP Congress Collegium Internationale Neuro-Psychopharmacologicum / Leonard, Brian E (ur.).
Glasgow: Local Organizing Committee of the CINP, 1998. str. 347-347 (poster, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 16289 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Properties of recombinant alpha (1) beta (2) gamma (2s) form of the rat GABA-A receptor expressed in the 293 human embryonic kidney cell line
Autori
Peričić, Danka ; Mirković, Kety ; Jazvinšćak, Maja
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
XXIInd CINP Congress Collegium Internationale Neuro-Psychopharmacologicum
/ Leonard, Brian E - Glasgow : Local Organizing Committee of the CINP, 1998, 347-347
Skup
XXIInd CINP Congress Collegium Internationale Neuro-Psychopharmacologicum
Mjesto i datum
Glasgow, Ujedinjeno Kraljevstvo, 12.07.1998. - 16.07.1998
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
GABA-A receptor recombinant; binding; (3H)flunitrazepam; (3H)TBOB
Sažetak
GABA and thiopental enhanced, whilst flumazenil, clonazepam and diazepam displaced (3H)flunitrazepam bound to membranes from 293 human embryonic kidney cells stably transfected with alpha (1) beta (2) gamma (2s)form of GABA-A receptor. The Kd for (3H)flunitrazepam was decreased by GABA. Potent displacers of convulsant t-(3H)butylbicycloorthobenzoate (3H)TBOB were picrotoxin and GABA, while the affinities of thiopental and dehydroisoandrosterone 3-sulfate were in the micromolar range.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
