Naslov
Application of HLA Class II Polymorphism analysis to the study of the population structure of the Island of Krk, Croatia

Autori
Martinović, Irena ; Bakran, Maja ; Chaventre, Andre ; Janićijević, Branka ; Jovanović, Veljko ; Smolej Narančić, Nina ; Kaštelan, Andrija ; Grubić, Zorana ; Žunec, Renata ; Roberts, Derek F. ; Rudan, Pavao

Izvornik
Human biology (0018-7143) 69 (1997), 6; 819-829

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
HLA Class; population structure; population genetics; anthropology

Sažetak
The population structure of the northern Adriatic island of Krk, Croatia, was studied using PCR methodology and nonradioactive oligonucleotide hybridization for the analysis of HLA-DRBI , DRB3, DRB4, DRBS, DQA1, and DQB1 polymorphisms. Allele frequencies, genetic kinship (R), and genetic distances (E2) were computed, and correlations between distance (genetic, linguistic, geographic) and kinship (migration) matrices were examined. The results, reflecting past (micro-) evolutionary processes, indicate that ethnohistorical and sociocultural events rather than geographic distances are the primary determinants of today's population structure of the island.

Izvorni jezik
Engleski

Znanstvena područja
Etnologija i antropologija

POVEZANOST RADA