Pregled bibliografske jedinice broj: 15834
PIBF inhibits perforin relase from NK cells
PIBF inhibits perforin relase from NK cells // The Immunologist / Natvig, B. Jacob (ur.).
Kirkland, (WA): Hogrefe&Huber Publishers, 1998. (predavanje, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 15834 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
PIBF inhibits perforin relase from NK cells
Autori
Zsuzsa, Faust ; Laškarin, Gordana ; Rukavina, Daniel ; Szekeres-Bartho, Julia
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
The Immunologist
/ Natvig, B. Jacob - Kirkland, (WA) : Hogrefe&Huber Publishers, 1998
Skup
10th International Congress of Immunology
Mjesto i datum
New Delhi, Indija, 01.11.1998. - 06.11.1998
Vrsta sudjelovanja
Predavanje
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
Perforin; Pregnancy; Progesteron; PIBF
Sažetak
The majority of decidual NK cells contains PIBF and at the same time high amounts of perforin. Since perforin mediates NK activity, low decidual NK activity might be due to inhibition of perforin liberation. We have shown that a high percentage of decidual lymphocytes is double positive for CD56 and PIBF. PIBF inhibits NK activity of peripheral lymphocytes. This is due to a block of perforin release by activated NK cells thus might at least partly explain the low NK activity of decidual cells in spite of their high perforin content.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
